- Only a handful of the characters set to appear in the next season of “Grey’s Anatomy” have been there since the beginning.
- Meredith Grey (played by Ellen Pompeo) has experienced a lot of changes in her career since she first walked into Seattle Grace Hospital.
- Alex Karev (played by Justin Chambers) and Cristina Yang (played by Sandra Oh) are no longer on the show.
- Warning: Major “Grey’s Anatomy” spoilers ahead.
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There have been 16 seasons of ABC’s medical drama “Grey’s Anatomy,” but most characters from episode one are gone.
There have been tragic character deaths, devastating departures, exciting spin-offs, and more that’s pulled people away from the series over the years.
In fact, the show’s original intern class has only one character left on the show, and only three of the pilot characters are on track to appear on season 17.
Read on to see how the cast has changed from their first season to their most recent.
Warning: Spoilers for all 16 seasons of “Grey’s Anatomy” ahead.
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